Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0383287
PubChem CID
Molecular Formula
C21H22N8O2
Molecular Weight
418.461 g/mol
Synonyms/Alias
[CHEMBL2441436; SCHEMBL2731436; OMDQMYACEIXKDK-UHFFFAOYSA-N; BDBM50442601; 1-{4-[2-(2;1;3-benzoxadiazol-5-yl)ethyl]piperazin-1-yl}-2-[4-(1H-tetrazol-1-yl)phenyl]etha]
InChI Key
OMDQMYACEIXKDK-UHFFFAOYSA-N
InChI
InChI=1S/C21H22N8O2/c30-21(14-16-1-4-18(5-2-16)29-15-22-25-26-29)28-11-9-27(10-12-28)8-7-17-3-6-19-2...
IUPAC Name
1-[4-[2-(2,1,3-benzoxadiazol-5-yl)ethyl]piperazin-1-yl]-2-[4-(tetrazol-1-yl)phenyl]etha
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

53 57 0 0 0 0 0 0 0 0999 V2000
-1.7943 -0.2498 1.5529 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.3015 -0.5068 1.2858 C 0 0 0 0 0 0 0 0 0 0 0 0
0.2584 0.510...

Experimental Data

Activity Data

Target Ion Channel
G protein activated inward rectifier potassium channel 2/3
Uniprot Accession Number
Function
Inactive
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect

Experimental Conditions

pH
pH 7.4
Holding Potential
−70 to 70 mV mV
Temperature
22–24 °C
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
31
Rotatable Bonds
6
logP
1.1279
Complexity
111.386
TPSA (Ų)
106.07
H-Bond Donors
0
H-Bond Acceptors
9
Ring Count
5
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